I.M. NAD⁺ Injection (50mg)

NAD⁺ by Injection — What and Why

NAD⁺ (Nicotinamide Adenine Dinucleotide) is the coenzyme at the center of cellular energy production. It fuels the mitochondrial electron transport chain, activates sirtuin proteins involved in DNA repair and inflammation regulation, and serves as a substrate for PARP enzymes involved in genomic maintenance. NAD⁺ levels decline meaningfully with age — research suggests a decline of roughly 50% between the ages of 40 and 60 — which is associated with reduced cellular energy capacity and other hallmarks of aging.

The I.M. injection delivers 50mg of NAD⁺ directly into muscle tissue, from which it's rapidly absorbed into circulation. This is a lower dose than the 250mg or 500mg delivered by IV infusion, but with complete bioavailability, in a fraction of the time, and without an extended infusion session.

I.M. vs. IV NAD⁺ — Understanding the Difference

Both routes deliver NAD⁺ directly into circulation, bypassing the gut. The differences are dose and time.

The I.M. injection isn't a substitute for IV NAD⁺ at higher doses — the dose is substantially lower, so the systemic NAD⁺ elevation is proportionally smaller. It's better understood as:

• A maintenance dose between IV sessions for clients on a regular NAD⁺ protocol
• An accessible entry point for clients who want to experience NAD⁺ before committing to a full IV course
• A time-efficient option for clients with limited availability who want regular NAD⁺ support without a longer appointment
• An add-on to an IV drip session on the same visit for additional NAD⁺ support

What 50mg of NAD⁺ Supports

At 50mg I.M., the injection produces a meaningful but modest elevation in circulating NAD⁺ — supporting mitochondrial function, cellular energy metabolism, and sirtuin activity. The effect tends to be more subtle than a 250mg IV infusion and builds with regular use rather than producing a pronounced acute effect.

For clients using I.M. NAD⁺ as a maintenance dose between IV sessions, the injection helps sustain the elevated NAD⁺ baseline established by the IV course. For clients new to NAD⁺, it's a gentler introduction without the time commitment of IV therapy.

Who May Consider This Injection

• Clients on a NAD⁺ IV protocol who want to maintain elevated levels between sessions
• Clients who want to begin NAD⁺ supplementation with a lower dose and shorter session before progressing to IV infusion
• Clients with busy schedules who want regular NAD⁺ support without a longer IV appointment
• Clients combining a NAD⁺ booster with an IV drip on the same visit
• Clients over 40 who want to address age-related NAD⁺ decline as part of a longevity-minded routine and prefer the injection format

Frequently Asked Questions